There is nothing "ontological or metaphysical" in QFT. It is doing physics at very small regions of space [quantum mechanics] in which energies involved are extremely large [relativity]. The real question however is why one shouldn't consider expanding, so to speak, the concepts and methodology of Schrödinger's onto relativistic particles; in other words, why not simply quantize particles under extreme velocities nearing speed of light?
All good graduate texts deal with such questions and show the various non-physical situations we are driven into (for instance, Shankar's Principles of QM, 2nd ed.; see end of chapter 20). There are also more involved questions that require QFT in order to be answered, like that of causality, demanding that outside the light-cone propagation amplitudes should vanish.
And all these in the realm of physics as a science---not under some metaphysical umbrella.