Blood antigens -- pregnant mothers' blood types and infants' blood types

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SUMMARY

The discussion centers on the implications of blood type incompatibility between pregnant mothers and their infants, specifically focusing on Rh factor and ABO blood group systems. It is established that an Rh-negative mother carrying an Rh-positive child can lead to the development of Rh D antibodies, posing risks in subsequent pregnancies. The conversation also raises questions about the significance of ABO incompatibility, particularly when a B-positive mother carries an A-positive child, and why this is not as heavily emphasized in prenatal care compared to Rh factor screening.

PREREQUISITES
  • Understanding of Rh factor and its implications in pregnancy
  • Knowledge of ABO blood group system and its antigens
  • Familiarity with maternal-fetal blood mixing during delivery
  • Basic concepts of immunology related to antibodies
NEXT STEPS
  • Research the clinical guidelines for Rh factor screening in pregnancy
  • Explore the effects of ABO incompatibility on newborns
  • Learn about the management of Rh D sensitization in subsequent pregnancies
  • Investigate immunological responses related to maternal-fetal blood type differences
USEFUL FOR

This discussion is beneficial for obstetricians, midwives, medical students, and anyone involved in prenatal care and maternal-fetal medicine.

mktsgm
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I have a small question regarding pregnant mother's blood types and infant's blood types.

We all know the if an Rh-ve mother carries an Rh+ve child, there is a possibility that their blood may mix during the delivery.

This may induce some (Rh D) antibodies in maternal blood. In case the same mother happens to carry another Rh+ve child for the second pregnancy, the antibodies of the mother will create a lot of problems to both.

My doubt here is, say if the mother is B+ve and the child is A+ve, the same situation arises with respect to A,B,O antigens. Why this antigen/antibody axis does not create problem in pregnancy?
 
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Oh. Thank you very much.

But if so why we aren't much bothered about ABO compatibility of the parents? Even if screened, the parents are not generally told about this fact. Perhaps not to scare them...

We seem to insist only on the Rh type excessively...

Anyway thanks.
 

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