Can a Portable Biochemical Testing Device Revolutionize Disease Management?

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SUMMARY

The discussion centers on the potential for a portable biochemical testing device to revolutionize disease management by enabling on-the-fly testing of various hormones and biochemicals, specifically mentioning thyroid hormones T3 and T4. The feasibility of creating such a device, akin to those used by diabetics, hinges on the ability to accurately measure biomolecule concentrations through methods like IR/visual/UV absorption, utilizing the Beer-Lambert law. Identifying unique absorption/emission lines for target compounds or employing specific reagents to enhance detection is crucial for the device's effectiveness.

PREREQUISITES
  • Understanding of Beer-Lambert law for concentration measurement
  • Knowledge of IR/visual/UV absorption techniques
  • Familiarity with biochemical testing methods
  • Basic principles of molecular spectroscopy
NEXT STEPS
  • Research advancements in portable biochemical testing technologies
  • Explore methods for identifying unique absorption/emission lines in biomolecules
  • Investigate the development of reagents for specific biomolecule detection
  • Learn about the applications of molecular spectroscopy in medical diagnostics
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Healthcare innovators, biomedical engineers, and researchers focused on developing diagnostic tools for disease management will benefit from this discussion.

TheEzEzz
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Hi all, I was thinking recently about insulin testing, and whether the convenience could be extended to other hormones and biochemicals in the body. For instance the thyroid molecules T3 and T4. It seems like a device capable of testing for the level of these molecules on the fly would be extremely useful for people with thyroid disease, and other tests may prove useful for other diseases as well.

My question is, how easy would it be to create a device, similar to what diabetics use, that could test for a large array of compounds in human blood and return their concentration?
 
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Well the difficulty depends on the molecule I suppose.

The simplest and cheapest way to determine the concentration of a biomolecule would have to be measuring IR/visual/UV absorption (or emissions) for some characteristic wavelength and use your basic Beer-Lambert law (or perhaps better, an empirical absorption-concentration curve).

The question there would be if you can identify an absorption/emission line unique to your target compound. (or at the very least, that the other compounds contributing to the absorption/emission would have relatively constant concentrations) Or you could find a reagent which, when added, would bind to your target molecule and create a characteristic line.
 

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