Can anyone help me with ny of these 4 genetics questions?

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This discussion focuses on genetic mapping and phenotypic ratios in Drosophila and mice. The genes for mahogany eyes and ebony body are located 25 map units apart on chromosome III, leading to specific expected phenotypes in offspring from various crosses. The discussion also covers sex-linked loci A and B, which are 20 map units apart, and the expected phenotypic frequencies in male and female offspring. Additionally, the expected number of chiasmata in mouse oocytes and the calculation of map distance between light and straw loci in Drosophila are addressed, with participants providing specific answers and methodologies.

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  • Understanding of genetic mapping and map units
  • Knowledge of Drosophila genetics and sex-linked traits
  • Familiarity with phenotypic ratios and expected offspring calculations
  • Experience with meiotic processes and chiasma formation
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  • Study Drosophila genetic mapping techniques and methodologies
  • Learn about sex-linked inheritance patterns in genetics
  • Explore the concept of map distance and its calculation in genetic studies
  • Investigate the role of chiasmata in genetic recombination and meiosis
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Genetics students, researchers in molecular biology, and anyone interested in understanding genetic mapping and inheritance patterns in model organisms like Drosophila and mice.

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1. The genes for mohogany eyes and ebony body are approximately 25 map units apart on chromosome III in Drosophila. Assume that a mahogany-eyed female was mated to an ebony-bodied male and the resulting F1 phenotypically wild type females were mated to mahogany, ebony males. Of 1000 offspring, what would be the expected phenotypes and in what numbers would they be expected?

2. Given that loci A and B in Drosophila are sex-linked and 20 map units apart, what phenotypic frequencies would you expect in male and female offspring resulting from the following crosses? (Assume A and B are dominant to a and b, respectively):
(a) AaBb(cis)female X ab/Y male
(b) AaBb(trans) X ab/Y male
(c) aabb female X AB/Y male

3. Assume that there are 12 map units between two loci in the mouse and that you are able to microscopically observe meiotic chromosomes in this organism. If you examined 200 primary oocytes, in how many would you expect to see a chiasma between the two loci mentioned above?
I got 2 for an answer. Is that correct?

4. Phenotypically wild F1 female Drosophila, whose mothers had light eyes(Lt) and fathers had straw(stw) bristles produced the following offspring when crossed to homozygous light-straw males:
phenotype: number:
light-straw 22
wild 18
light 990
straw 970
total: 2000
Compute the map distance between light and straw loci.
I got 1.1 mu for an answer. Is that correct?

Thanks in advance for any help.
 
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