Can DNA Tests Distinguish Between Grandfathers and Their Brothers?

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Point Conception
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Can a DNA test differentiate between a females maternal grandfather and maternal
grand uncle, the grandfathers brother.
And also can a DNA test differentiate between this same females paternal grandfather and
paternal grand uncle.
In otherwords can this females paternal and maternal grandfather be confirmed by testing
her mother and father ?
 
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Yes. A father and an uncle have different DNA. Which one is which can therefore be determined.