Determining molecular resonance frequencies

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Cloud Wolf
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I have been searching for ways to calculate resonance frequencies of complex molecules. I know that doing so is extremely complex, especially if that molecule contains many elements, but perhaps it could be feasible to target a specific component of a large molecule, such as a nucleus in a cell, through means of resonant frequencies thus being able to split or manipulate the molecular structure. I would be grateful for any help.
 
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Your question doesn't make much sense from the viewpoint of hard science, where terms are defined in an exact way. A molecule has rotational, vibrational, electronic and nuclear resonance frequencies and all of them are calculated/estimated with different methods. A living (animal, plant, fungus, bacterial) cell is definitely not a single molecule.
 
Sorry for the confusion. I meant to say the electronic frequency of a specific protein within a molecule, or a simple structure like H2O, however I would prefer not to discus H2O since many have already found this