Do Macrophages Have Both MHC I and MHC II Molecules on Their Surface?

[jayadds]

Hi all,

I was just wondering, are there MHC I molecules on the surface of a macrophage? According to my textbook, this is the rule:

All nucleated cells have MHC I
Dendritic cells, macrophages and B cells have MHC II

Can macrophage be considered as a nucleated cell? If so, does that mean a macrophage has both MHC I and II molecules on its surface?

Many thanks,
Jay

 

[Curious3141]

Yes, macrophages (and other Antigen Presenting Cells) have MHC I in addition to MHC II.