There are very few circumstances where I'd apply an adhesive dressing to a blister. I would generally go with a non-adherent, or at the very most a low-adherent dressing so that you don't damage the tissue when changing the dressing. The circumstances would vary on the type and location of blister, but I fail to see a good excuse to use an adherent dressing on one.
As for flour, Ouabache got it; it just soaked up the moisture in the wound. It won't be clean, and it definitely won't be sterile.
Once your blister is clean (warm soapy water) dress it with a non-adherent dressing, keep it covered, and change it regularly. Don't burst a blister if you can help it, though I'll admit there are circumstances when this is not practical. A blister is an example of how good the body can be at protecting itself; all that pus is effectively a sterile cushion protecting the wound whilst the body repairs itself.
If you do need to burst a blister (a few instances I've been in involve being stuck out on the moors with no way of getting home other than walking on a badly blistered foot), thoroughly clean the area first, preferably with an antiseptic fluid, drain with a sterilised needle, and be damn sure you dress it properly afterwards. Never burst a blood blister.