In special relativity, the equation F=ma is not applicable at high speeds, particularly as velocities approach the speed of light, making F=dp/dt a more accurate representation of force. The concept of relativistic mass is considered outdated and can lead to confusion; instead, mass is treated as invariant and independent of the observer's frame of reference. While Newton's equations are sufficient for many practical applications, they become less accurate at high energies or precision levels, such as in GPS technology. The proper formulation of momentum and energy in relativity involves four-vectors and incorporates both rest mass and relativistic effects. Understanding these principles is crucial for accurately describing motion at relativistic speeds.