Find a Fatal Disease for 25 Year Olds with Environmental Causes

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SUMMARY

The discussion centers on identifying a fatal disease for a fictional 25-year-old character, emphasizing environmental causes rather than genetic factors. Participants suggest various diseases, with a focus on Acute Myeloid Leukemia (AML) due to its rapid progression and potential for chronic management. Other diseases considered include Bernhardt's Disease and chronic hepatitis, with an emphasis on ensuring the character remains active and has a plausible, albeit grim, prognosis. The conversation highlights the importance of balancing scientific accuracy with narrative needs in storytelling.

PREREQUISITES
  • Understanding of Acute Myeloid Leukemia (AML) and its subtypes
  • Knowledge of environmental toxins and their health impacts
  • Familiarity with chronic diseases and their management
  • Basic concepts of prognosis and disease progression
NEXT STEPS
  • Research the characteristics and prognosis of Acute Myeloid Leukemia (AML)
  • Investigate the implications of environmental toxins on health
  • Explore chronic hepatitis and its potential complications
  • Study Bernhardt's Disease and its relevance to the narrative
USEFUL FOR

Writers, medical professionals, and anyone interested in the intersection of storytelling and medical accuracy, particularly in creating realistic portrayals of diseases influenced by environmental factors.

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Ideally with:
  1. no neuromotor or cognitive losses
  2. diagnosable at least two years before death with a (literal) deadline
  3. may or may not cause hallucinations
  4. may or may not cause intense pain (periodic or chronic)
    -to get him hooked to methadone (optional)​
  5. a very high risk last moment cure/treatment (optional...keeping my options open)
  6. preferably caused by an environmental toxin
  7. definitely not genetic
  8. character would be 25 year old or less

I am thinking leukaemia but have very less idea about how much it fits the above...
Any comments or ideas?
 
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Leukaemia doesn't seem to fit. I personally know (or knew) three people who contracted it. Age range 30 to 50. Two died within a few weeks of being diagnosed, the other is still alive and in remission 20 years later - but he is the sort of guy who takes the view that he can cause more aggravation to the rest of the world by staying alive, and that's sufficient motivation for not dying!

In other words, it seems as unpredictable as any other form of cancer.
 
Why not the rare Bernhardt's Disease?
 
AlephZero said:
Leukaemia doesn't seem to fit. I personally know (or knew) three people who contracted it. Age range 30 to 50. Two died within a few weeks of being diagnosed, the other is still alive and in remission 20 years later - but he is the sort of guy who takes the view that he can cause more aggravation to the rest of the world by staying alive, and that's sufficient motivation for not dying!

In other words, it seems as unpredictable as any other form of cancer.

I read up on leukaemia, there are two types acute and chronic. Acute acts faster chronic's generally slower. [strike]AML[/strike] ALL seems to fit better (in terms of incurability and [STRIKE]non-longevity[/STRIKE]) I will have to see the sub-types to decide what I kill him with. I feel evil.
 
Last edited:
Vanadium 50 said:
Why not the rare Bernhardt's Disease?

:bugeye:
Greg's sick?
The only definition I found had listed wearing skinny pants/belts as a cause:
http://medical.dictionary.net/bernhardt's disease
http://en.wikipedia.org/wiki/Meralgia_paraesthetica
I need the guy to move around* (a lot) and die (once...maybe twice).
(I am kind of fixated on leukaemia because I want him to joke about being 'white blooded'.)
*I am considering chronic leukaemia for this reason, I definitely don't want him chained to a bed.
 
The point is that you can make something up that has exactly the right properties.
 
What about a lung disease caused by something like asbestos.
 
Vanadium 50 said:
The point is that you can make something up that has exactly the right properties.
I don't mind stretching the science to fit the story but I would rather not tear it apart altogether. It should be plausible enough that if I post it in the med. sci. forum I wouldn't get banned.
:biggrin:
(The story is set in this decade or perhaps the last.)
leroyjenkens said:
What about a lung disease caused by something like asbestos.
I am afraid not, respiratory diseases seem to be all caused either by infections (treatable and if not too quick to kill) or toxins which won't fit the story too well; non-smoker and not an outdoor guy.

I have ruled out infectious diseases with exception to AIDS, most toxins and auto-immune diseases; AIDS, worms near the brain stem and aneurisms will be my fall back in case nothing else works.
I am back fixating on AML, diagnosed before the start of the story and in partial remission. I will go read up some oncology texts and see what I can do to keep it incurable and yet moderate enough to justify him being an outpatient.
 
How about something like a hepatitis? Doesn't necessarily fit with a literal deadline but it could be like a chronic hepatitis case which can start getting worse and have some MD tell him he has XX years to live. Prognoses are pretty much educated guesses anyway, no one can really give a literal deadline for death from disease. There is encephalopathy towards the end of the disease if memory serves. You'd need to do some more research but it may fit the bill.
 
  • #10
Thanks, will look into it.
:smile:
 
  • #11
Just to elaborate why I chose that route. Last minute cure might be a liver transplant, its pretty risky etc. Its not genetic but can be passed from mother to fetus and can be aggravated by boozing and/or stuff like tylenol and maybe others.
 

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