Genetics problems- punnett squares

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SUMMARY

This discussion focuses on solving genetics problems using Punnett squares. The first problem involves calculating the probability of Charles and Elaine having a child with cystic fibrosis, given that Elaine's brother has the genotype aa, indicating both parents are carriers. The second problem analyzes the offspring of a cross between a green tall pea plant and a yellow short plant, concluding that the parent plants likely have the genotype YyTt based on the observed phenotypic ratios. The discussion emphasizes the importance of understanding genotypes and probabilities in genetic inheritance.

PREREQUISITES
  • Understanding of Mendelian genetics and Punnett squares
  • Knowledge of dominant and recessive alleles
  • Familiarity with genotype notation (e.g., AA, Aa, aa)
  • Ability to calculate phenotypic ratios from genetic crosses
NEXT STEPS
  • Study the principles of Mendelian inheritance in depth
  • Learn how to construct and interpret Punnett squares for various genetic scenarios
  • Explore the concept of carrier status in genetic disorders
  • Investigate advanced genetic concepts such as epistasis and polygenic inheritance
USEFUL FOR

Students studying genetics, educators teaching biology, and anyone interested in understanding genetic probability and inheritance patterns.

colton4286
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I need help with these:

1. Charles was married once before, & he and his first wife had a child who suffers from cystic fibrosis. His current wife Elaine's brother died of cystic fibrosis. What is the probability that Charles & Elaine will have a baby with cystic fibrosis?

Let's say A= normal, a= has cystic fibrosis. If Elaine's brother's genotype is aa, that means both parents carry the recessive allele. From here, I am stuck. How do I know whether the parents are both heterozygous or if one parent is homozygous recessive & the other parent heterozygous. How do I know if Elaine is AA or Aa?

2. T= tall, t= short; Y= yellow, y= green
A green tall pea plant is crossed with a yellow short plant. Their offspring are as follows:

77 green short
81 yellow short
79 yellow tall
84 green tall

What are the genotypes of the parent plants?

Since there are 4 different phenotypes, I'm assuming that the offspring came from the selfing of a plant with genotype YyTt. I found the phenotypic ratios from this data and they all seem fairly close to each other, almost the same (24%, 25%, 25%, 26%) but don't know where to go from here.
 
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colton4286 said:
I need help with these:

1. Charles was married once before, & he and his first wife had a child who suffers from cystic fibrosis. His current wife Elaine's brother died of cystic fibrosis. What is the probability that Charles & Elaine will have a baby with cystic fibrosis?

Let's say A= normal, a= has cystic fibrosis. If Elaine's brother's genotype is aa, that means both parents carry the recessive allele. From here, I am stuck. How do I know whether the parents are both heterozygous or if one parent is homozygous recessive & the other parent heterozygous. How do I know if Elaine is AA or Aa?
You don't know. You have to factor that into your determination of the probability. She could be a carrier or she might be completely unaffected, so you have to work out the probabilities with both choices.

2. T= tall, t= short; Y= yellow, y= green
A green tall pea plant is crossed with a yellow short plant. Their offspring are as follows:

77 green short
81 yellow short
79 yellow tall
84 green tall

What are the genotypes of the parent plants?

Since there are 4 different phenotypes, I'm assuming that the offspring came from the selfing of a plant with genotype YyTt. I found the phenotypic ratios from this data and they all seem fairly close to each other, almost the same (24%, 25%, 25%, 26%) but don't know where to go from here.
Unless there's more to the problem that you haven't shown, there's nowhere to go from here. You've found the answer already.
 

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