To prevent a 500-gallon plastic septic tank from floating in Houston's groundwater, it is crucial to maintain the tank's capacity full to counteract buoyancy, especially if flooding is a risk. The tank should ideally be buried at least 4 feet below the surface to utilize earth cover, which helps resist flotation even when submerged. An engineering safety factor of at least 1.1 is recommended, calculated by comparing resisting forces to uplift forces. Resisting forces can be increased by adding more soil cover, constructing a concrete slab, or using deadmen and straps. Implementing helical anchors and straps can also enhance stability against flotation.