SUMMARY
The discussion centers on calculating the theoretical yield of ATP from the oxidation of one mole of glucose. It is established that the delta G for glucose oxidation is -916 kJ/mol, while the formation of ATP from ADP and phosphate has a delta G of +31.4 kJ/mol. Therefore, the maximum number of moles of ATP that can be produced from one mole of glucose is determined by the energy balance between these two reactions. The conclusion is that approximately 30 to 32 moles of ATP can be synthesized from one mole of glucose under standard physiological conditions.
PREREQUISITES
- Understanding of thermodynamics, specifically Gibbs free energy (delta G)
- Knowledge of cellular respiration and ATP synthesis
- Familiarity with biochemical equations involving ADP and ATP
- Basic principles of energy balance in biochemical reactions
NEXT STEPS
- Research the process of glycolysis and its ATP yield
- Learn about the Krebs cycle and its contribution to ATP production
- Study oxidative phosphorylation and its role in ATP synthesis
- Explore the concept of energy coupling in biochemical reactions
USEFUL FOR
This discussion is beneficial for biochemistry students, educators, and anyone involved in metabolic studies or energy production research in biological systems.