What Are the Basic Pathologies Related to Sugar Metabolism in Humans?

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SUMMARY

The discussion focuses on the basic pathologies related to sugar metabolism in humans, specifically diabetes mellitus and conditions of hypo/hyperglycemia. Diabetes mellitus is characterized by hyperglycemia due to insufficient insulin, which impairs glucose uptake by cells. The user seeks clarification on how these conditions relate to metabolic processes such as glycolysis, gluconeogenesis, and glycogenolysis. The conversation emphasizes the need for a clear understanding of these biochemical pathways to connect the symptoms and treatments of sugar metabolism disorders.

PREREQUISITES
  • Understanding of diabetes mellitus and its types
  • Knowledge of glycolysis, gluconeogenesis, and glycogenolysis
  • Familiarity with insulin's role in glucose metabolism
  • Basic biochemistry concepts related to metabolism
NEXT STEPS
  • Research the mechanisms of insulin action in glucose uptake
  • Study the biochemical pathways of glycolysis and gluconeogenesis
  • Explore the physiological effects of hypo and hyperglycemia
  • Learn about glucagon's role in glycogenolysis and fat metabolism
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Students of biochemistry, healthcare professionals, and anyone interested in understanding the metabolic disorders related to sugar metabolism, particularly diabetes and its associated pathologies.

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Biochemistry pathologies.. ??

Hey guys..

I'm trying to set straight in my mind the basic pathologies relating to sugar in the human. Mainly, the various types of diabetes and hypo/hyperglycemia.

We covered the basics in my biochemistry class, but we did it all so fast that I got lost with all the talk of gluconeogensis and glycogenolysis and glycolysis, etc. Everything is so confused in my mind that the other night I was watching a movie and the little girl needed her glucagon shot and I had to figure out what pathology she had..

May someone please just take the above diseases and breifly say what they are a deficiet of?

(I promise this isn't a homework question or anything, we've left this material behind and are on heme synthesis now ... I just want to have these things straight..)

Like.. Diabetes mellitus results in hyperglycemia because of the lack of insulin to take glucose out of the blood and into the cells.. So how does this relate to glycolysis, gluconeogensis, or glycogenolysis?

Or when you are a bit hypoglycemic, and you release glycogen to beak down fats (b-oxidation?)..??

I just need a little help weaving everything together.. I would really appreciate any insight into this.

Thank you
 
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Found this it might help a little:smile:

http://www.elmhurst.edu/~chm/vchembook/604glycogenesis.html
 
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