What Discovery Did You Find Most Interesting or Surprising?

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Discussion Overview

The discussion revolves around personal reflections on scientific discoveries that participants found most interesting or surprising during their lives. It encompasses a range of topics from genetics to astrophysics, highlighting individual experiences and insights related to various scientific concepts.

Discussion Character

  • Exploratory
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant expresses surprise at the realization that Fermat's proof could not fit in the margin, suggesting a personal connection to mathematical history.
  • Another participant shares their amazement at the discovery of Hox clusters in vertebrates and insects, emphasizing the evolutionary implications and the complexity of genetic regulation in establishing the Anterior-Posterior body axis.
  • A different participant mentions the detection of gravitational waves at LIGO, noting its significance as a validation of Einstein's predictions, although they did not find it surprising.

Areas of Agreement / Disagreement

The discussion does not present a consensus, as participants share varied personal experiences and reflections on different scientific discoveries without resolving any disagreements.

Contextual Notes

Participants reference specific scientific concepts and discoveries without delving into the technical details or implications of those discoveries, leaving some assumptions and interpretations unexamined.

Who May Find This Useful

Individuals interested in personal narratives related to scientific discoveries, as well as those exploring the impact of significant scientific milestones on public understanding and appreciation of science.

BillTre
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Which Scientific Discovery (that you've experienced during your life) has been the most interesting or surprising to you, based on your prior knowledge?

And why?
 
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BillTre said:
Which Scientific Discovery (that you've experienced during your life) has been the most interesting or surprising to you, based on your prior knowledge?
Why don't you start us off :)
 
BillTre said:
Which Scientific Discovery (that you've experienced during your life) has been the most interesting or surprising to you, based on your prior knowledge?
That Fermat's proof really did not fit on the margin.
 
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Greg Bernhardt said:
Why don't you start us off :)
Had to make it shorter.

When I was in High School, I was pretty amazed at Plate Tectonics explaining a lot of things I found interesting. But that was not really a thing I was current on. It was more of a gradual dawning.

So I would say it was probably when this paper showed that Hox clusters in vertebrates (deuterostomes) and insects (protostomes) shared so many of the same properties (important for establishing the Anterior-Posterior body axis in bilaterally symmetrical animals).

Hox clusters are large genetic regions, conserved for possibly more than 550 MY (depending on time of origin of the bilaterally symmetric metazoans). Hox gene expression and mutant phenotypes indicating they are involved in assigning cell fate along the A-P axis. This cellular process involves many different proteins from many different genes and instructs fruit fly cells how to develop based upon their position in the embryo; as a thoraic segment 1 leg cell, or a thoraic segment 2 leg cell for example. Genes at one end of a cluster affect the front of the embryo, genes at the other end affect back end of the animal. These clusters are very big and very complex and are very well conserved. This continuous selection, implies an essential function that can not be lost (like making the A-P axis).

To me, this indicates:
  • gastrulation (establishing the A-P axis & how mesoderm (muscle, bones, etc) forms) differences
  • between the protostomes (most invertebrates) and deuterostomes (vertebrates and echinoderms)
  • evolved in an already bilaterally symmetrical, two layered (endoderm and ectoderm) animal, after the front and back ends were (A-P (Anterior-Posterior) axis).
  • Perhaps a flatworm-like thing, like this. (Current flatworms are protostomes however, so would have to be different, unless deuterostomy is a state derived from the protostome situation.)
 
The detection of gravitational waves at LIGO. It was not surprising but a very exciting moment, becaude it came 100 years after Einstein's prediction, proving that he was really one smart dude.
 

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