Where Does Our Body's Bacteria Come From?

[binbots]

I was just wondering where all the bacteria in our bodies comes from? Does it enter the body through the mother during pregnancy? Also how does the body know how much to let in?

 

[HallsofIvy]

I was just wondering where all the bacteria in our bodies comes from? Does it enter the body through the mother during pregnancy? Also how does the body know how much to let in?

Much of it comes in through food or water- some in the air we breathe. The body does NOT "know how much to let in". But it can kill some of the bacteria. And the "beneficial" bacteria in the intestine is pretty much controlled based on how much food it gets.

 

[Andy Resnick]

I was just wondering where all the bacteria in our bodies comes from? Does it enter the body through the mother during pregnancy? Also how does the body know how much to let in?

You eat them (or drink them, as HallsofIvy mentioned). Several species of infant animals have their mother's feces for a first meal in order to get the bacteria into their gut.

 

[JorgeLobo]

Flora are established relatively early in life, much of it from maternal contact, and it will change during life. You'll have more bacterial/microbial cells in and on your body than human cells and their dynamic has to do with available space, substrate, competition with you and other microbe, etc.

Look up the term "microbiome."

 

[binbots]

Thanks everyone. So when we are born we are bacteria free. But without these bacteria we will die. That is just interesting to think about.

 

[JorgeLobo]

We probably won't die without them but we and they have evolved together so it won't be easy wthout them - one can sustain gnotobiotic (microbe-free) animals.

 

[bobze]

We probably won't die without them but we and they have evolved together so it won't be easy wthout them - one can sustain gnotobiotic (microbe-free) animals.

Actually we'd probably die without our bacteria. They preform a host of services for us, from helping in digestion to out-competing real "bad" bacteria. Our immune systems evolved with them as well and there is evidence that bacteria and parasites help "pacify" our immune system--Or better keep it occupied such that it doesn't start attacking self-antigens.

 

[Andy Resnick]

Actually we'd probably die without our bacteria. They preform a host of services for us, from helping in digestion to out-competing real "bad" bacteria. Our immune systems evolved with them as well and there is evidence that bacteria and parasites help "pacify" our immune system--Or better keep it occupied such that it doesn't start attacking self-antigens.

In practice, we would probably die. However, germ-free animals are an important component of biomedical research, and so it is clearly possible to live without bacteria present.

 

[Q_Goest]

In practice, we would probably die. However, germ-free animals are an important component of biomedical research, and so it is clearly possible to live without bacteria present.

Hi Andy, do these germ-free animals have no bacteria in the gut either?

 

[bobze]

In practice, we would probably die. However, germ-free animals are an important component of biomedical research, and so it is clearly possible to live without bacteria present.

I agree Andy. The requirements that germ-free animals must be kept under (or even gnobiotic animals where the few strains that do live on them are known) aren't realistic to keeping a human being under. A bacteria free human, outside of a science-fiction novel, is a dead human.

 

[bobze]

Hi Andy, do these germ-free animals have no bacteria in the gut either?

There are animals that can be completely germ free which can used to study the effects of how a single type of bacteria introduced interact with their physiological and biological functions. Gnobiotic animals are animals with a known limited number of strains of microorganisms living on/with them.

 

[Andy Resnick]

Hi Andy, do these germ-free animals have no bacteria in the gut either?

Based on the little knowledge I have (I don't do whole-animal research), I think the answer is 'no'. Those animals are kept on a highly regulated diet:

http://www.labdiet.com/products.html

and housed in sterile environments:

http://books.google.com/books?id=Gi...wBA#v=onepage&q=sterile mouse bedding&f=false

(the section on 'deriving' gnobiotic mice is worth reading also)

 

[JorgeLobo]

No bobze - gnotobiotic concept also includes germ-free animals.

 

[bobze]

No bobze - gnotobiotic concept also includes germ-free animals.

Jorge, I didn't say anything that disagreed with that...gnotobiosis (to "know life") refers to knowing an organisms microbial flora--Be that a few strains of known microorganisms colonizing the organism, or "knowing" it posses no microbial flora. Obviously then Jorge, the set "germ-free" belongs to the set gnotobiotic...But thanks for playin anyway!

 

[mishrashubham]

I thinks microbiota is a genus of evergreen coniferous shrub in the cypress family Cupressaceae, containing only one species, Microbiota decussata.

The thread is not about the genus microbiota but about gut flora, microbes present in our intestines.