I won't do the calculation, but several effects come to mind:
1) Time delay - It takes about 8.5 minutes for light to reach the sun from here, so you'd have to take the sun's motion during that time into account.
2) Atmospheric refraction - The sun's actual position is shifted from the apparent one by the bending of its light in the atmosphere. Although the laser beam would be bent as well, this bending is wavelength-dependent, so the shift wouldn't be the same. Also, the Earth would be at a different point in its orbit when the laser's light was bent, so the path would be slightly different.
3) Aberration - The sun's apparent position is shifted due to the Earth's motion. This is the same effect that has to be considered when measuring stellar parallaxes.
4) GR effects - The light beam will follow a geodesic in spacetime, not a straight path in space. The difference should be very small, but non-zero.
In other words, you couldn't just point the beam at the center. I think that would get you pretty close, though.