Which Monosaccharides are Indigestible to Humans?

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Discussion Overview

The discussion revolves around the question of which monosaccharides are indigestible or un-metabolizable by humans. Participants explore the characteristics of monosaccharides in relation to human digestion, considering both general cases and specific intolerances.

Discussion Character

  • Exploratory
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • Some participants note that lactose-intolerant individuals cannot digest lactose and that humans cannot digest cellulose, prompting a broader inquiry into monosaccharides.
  • It is mentioned that cellulose is a polymer, leading to a clarification that the focus should be on monosaccharides specifically.
  • One participant asserts that any monosaccharide that can be converted to fit into glycolysis can be metabolized, suggesting that all naturally occurring monosaccharides in food are metabolizable.
  • Another participant proposes that lab-created monosaccharides might be indigestible due to the absence of necessary enzymes in the human body.
  • A question is raised regarding the structural characteristics of monosaccharides that might render them un-metabolizable, including the potential influence of L or D structure and enzyme recognition.

Areas of Agreement / Disagreement

Participants express differing views on the digestibility of monosaccharides, with some asserting that all naturally occurring monosaccharides are metabolizable while others suggest that certain structures may lead to indigestibility. The discussion remains unresolved regarding specific examples of indigestible monosaccharides.

Contextual Notes

Participants highlight the importance of enzyme specificity and structural characteristics in determining the metabolizability of monosaccharides, but no consensus is reached on definitive examples or criteria.

bomba923
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For example, lactose-intolerant humans cannot process/digest lactose.
Neither can we digest cellulose.

--------------------------------------
But for the most "tolerant" humans,
are there certain monosaccharides that humans cannot digest?

*What monosaccharides are inedible to humans?
(and not just for those who are lactose-intolerant)
:redface:
 
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They are still edible, but just not metabolizable. Cellulose is a polymer.
 
quasi426 said:
They are still edible, but just not metabolizable. Cellulose is a polymer.

Yes, I know, cellulose (a polysaccharide) is a polymer of glucose :rolleyes:

But my question is:

What monosaccharides cannot be metabolized by humans?

Not considering special "-intolerant" types, which monosaccharides simply cannot be metabolized by humans?
:blusing: Even among the most *tolerant* types?
 
Last edited:
Any monosaccharide that can be converted so it can fit into glycolysis can be metabolized. None of the monosaccharides naturally found in food are un-metabolizable. If we can break down the polysaccharide, we can find a way of converting all the monosaccharides into energy (although sometimes more and sometimes less than glucose). There probably are monosaccharides you can make in a lab that we can't digest because we don't have the enzymes to convert them into something usable.
 
does it have anything to do with L or D structure?the one that cannot be metabolised are the one that are not recognised by the normal body enzymes (or due to lack of that enzyme)...and since they're specific for one kind of structure...correct me if I'm wrong!
 
By the way,

*What features would an un-metabolizable monosaccharide possess?

*What (structural) characteristics might cause a monosachharide to be un-metabolizable?

:smile:
 

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