Why Does Mixing CuSO4 and H2O Release Heat?

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Mixing CuSO_4 and H_2O, heat was produced during the reaction. Why did that happen?
 
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the simplest answer is that when the cupper and sulfate ions dissociated energy was released.
 
The simplest answer is slightly wrong here, as if you will mix CuSO4.5H2O with water you will not observe substantial heat evolving.

Look for heat of hydration.