Crude oil can be easily processed into a variety of fractions (through "fractionation") into mostly, simply connected oxygen-free hydrocarbons, the paraffins, ranging from C=5 to C=40 in length.
For fuel, it is easily "cracked" to yield higher proportions containing weights around C=8. Gasoline has mostly octane, or there abouts. Gasoline is a high density energy source in a liquid form convenient for storage, delivery and conversion. Heavier fractions can be used for jet fuel and fuel oil. Half the energy source doesn't require storage, but comes out of the air, which is readily available.
Most synthesis of plastics, drugs, dyes and other organic chemical compounds, require as precursors, the shorter hydrocarbons I think, so that natural gas is probably also a source. You could look this up as easily as I, I think. In any case one would want uniform, short molecules that are oxygen-free for the most part.