Xenopus and Zebrafish as Models of Human Disease

[Soaring Crane]

For zebrafish and Xenopus, are there currently any effective gene knockout strategies? From literature, these two organisms have effective gene knockdown strategies in practice.

Thanks for any help.

 

[Monique]

Yes, with CRISPR/Cas9 technology: https://www.addgene.org/CRISPR/