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Jan21-13, 07:07 PM
P: 640
Quote Quote by Shisnu View Post
If you used a saline solution with a larger concentration of salt then it would act to induce a shift in fluid from the intracellular to the extracellular space due to the osmotic gradient (hypertonic saline is therefore effective at reducing intracranial pressure as it decreases brain water).
Hey, Thanks for the reply However in this scenario if I add salt into intravascular compartment, wouldn't that make it more hypertonic, so shouldn't water from outside come in, instead. Why have you stated the opposite? Did I missunderstand something.

EDIT: Oh wait are u saying? If I add salt to blood vessels, water from red blood cells for example would come out increasing intravascular compartment, then this excess water would go out of the intravascular compartment due to increase hydrostatic pressure inside the vessels, so you lose some water from crystalloids.