Recent content by Manish7

  1. Manish7

    Disorders which have signs of cyanosis

    Can anyone explain why cyanosis does not occur in anemic patients while it is significantly present in patients of polycythemia vera and COPD (chronic obstructive pulmonary disease) ??
  2. Manish7

    Changes seen in JVP due to Constrictive Pericarditis

    Can anyone explain me why there is prominent "x" and "y" descent in constrictive pericarditis and also why "y" descent is absent in Cardiac Tamponade ?
  3. Manish7

    Which diuretic causes more hyponatremia?

    can someone tell me why thiazide group of diuretics cause more hyponatremia as compared to loop diuretics despite the fact that loop diuretics cause more sodium loss as compared to thiazide drugs ??
  4. Manish7

    Can Lowering Body Temperature Kill Viruses Like HIV?

    Decreasing the body temperature will make the virus dormant (inactive) but will not kill it. Low temp. will kill it only when it is outside the cell or in environment.
  5. Manish7

    i am back from Hibernation.

    i am back from Hibernation.
  6. Manish7

    Pulmonary Oedema & Dexamethasone in Mountain Sickness

    Hello everyone reading it, can you just help me understanding why pulmonary oedema occurs during mountain climbing ,when there is rapid ascent? Also why Dexamethasone is used ,although not curative but palliative?
  7. Manish7

    Grafts used in Coronary Bypass surgery.

    I replied in the previous thread of mine.
  8. Manish7

    How Atherosclerosis cause endothelial injury?

    This isn't any homework, I am just asking my query when going through CVS Pathology.
  9. Manish7

    How Atherosclerosis cause endothelial injury?

    Atherosclerosis causes accumulation of lipids (cholesterol, cholesterol esters) within the intima of major vessels."Robbins and Cotran, 8 edi." says it is due to endothelial injury rather endothelial dysfunction,which leads to increased permeability, inc. expression of adhesion molecules...
  10. Manish7

    Grafts used in Coronary Bypass surgery.

    Previously graft for coronary artery bypass was great saphenous vein (GSV) still being used,but now Internal mammary artery(IMA) is the graft of choice. Because IMA doesn't atherosclerose at alland all the vessels of upper limb, and its life is upto 10years. I need to put up query why it is...
  11. Manish7

    What is the effect of thiazide diuretics on GFR?

    Having a little query that what is the effect of diuretics (both thiazides and loops) on GFR ? Athough katzung 12th edi. says loops _ no effect on gfr, but it is silent on thiazides ? no thiazides are given when GFR <30ml/min except metolazone while loop diuretics are given in heart failure...
  12. Manish7

    Holding Your Breath and Brain Damage

    How can this occur ?
  13. Manish7

    Why Doesn't Tetanus Infection Cause an Inflammatory Reaction?

    As i was passing reading tetanus and its causating bacterium ,pathogenesis, ,clinical manisfestations, i found that it is present as spores in soil and gains entry in body through wounds (except in neonatal tetanus ), germinates and then starts secreting toxin tetanospasmin leading to...
  14. Manish7

    Why in fever or increased temperature body's platelets are reduced?

    i have observed that during fever or increased body temperature , serum platelets are reduced. i have seen in patients of viral fever,dengue(its obvious) etc platelets are reduced but not to that extent that it can cause internal bleeding or haemorrhage or petechiae ? why is this so ?
  15. Manish7

    Iron Pill Overdose: Is Deferasirox Safe and Effective in Treating Iron Toxicity?

    you have not focussed , that deferasirox is approved by FDA in 2005.also the symptoms of iron toxicity in acute condition like vomit.,diarrhoea,pain abdomen,coma are much more severe than its side efeects especially in developing countries but not in developed nations. also note that...
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