how can you expect a 105 pound woman to use hand-to-hand combat to defend herself from a 250 man determined to rape her? Or how about you versus 4 guys attacking you and beating you with baseball bats? Being armed levels the field to some extent. A big strong bad guy and a 100 pound grandma are much more equal being armed than going at it in hand-to-hand combat.
This is the one part of the argument I understand, but don't accept. Or at least, I don't see it reflected in the crime stats. If fire arms really did 'level the playing field' you'd expect there to be more rapes / attacks in places with stricter gun control laws. This isn't the case as far as I've seen so I can't accept that as a valid argument.