Aqueous solution of tolyltriazole

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SUMMARY

The discussion centers on the challenges of creating a stable aqueous solution of tolyltriazole, which is known for its low solubility in water. Attempts to enhance solubility using sodium hydroxide and increasing temperature were unsuccessful, leading to precipitation upon cooling. Experts conclude that there is no straightforward method to achieve a stable aqueous solution of tolyltriazole, and suggest exploring mixed solvents tailored to specific applications, although this requires further information on concentration and intended use.

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Chemists, chemical engineers, and researchers involved in formulation development or studying the solubility of organic compounds will benefit from this discussion.

zehtab
TL;DR
how can i make an Aqueous solution of tolyltriazole?
How can i make an Aqueous solution of tolyltriazole?
i need to make an Aqueous solution of tolyltriazole, but its solubility in water i very low. It dissolves with increasing temperature (50(c)) and redeposits with decreasing temperature. Some sodium hydroxide was added to the solution to improve the solubility, but again, after 2 hours, precipitation is formed by lowering the temperature. What is a way to make a stable aqueous solution of tolyltriazole?
 
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zehtab said:
TL;DR Summary: What is a way to make a stable aqueous solution of tolyltriazole?
Tolyltriazole is a mixture of organic isomers. One would fully expect it to be highly insoluble in water, consistent with the results you quoted.

There is nothing you can do about it, no obvious way to prepare a stable aqueous solution of the material.

It is conceivable that a mixed solvent might work, but that is a completely different question and very dependent on the intended application.
 
Hyperfine said:
Tolyltriazole is a mixture of organic isomers. One would fully expect it to be highly insoluble in water, consistent with the results you quoted.

There is nothing you can do about it, no obvious way to prepare a stable aqueous solution of the material.

It is conceivable that a mixed solvent might work, but that is a completely different question and very dependent on the intended application.
Thanks a lot.
And what solvent mixture do you recommend?
 
zehtab said:
And what solvent mixture do you recommend?
Recommend based on what? Have you stated the desired concentration? No. Have you described the application? No. There is insufficient information to provide a reasonable recommendation.

Actually I do have a recommendation. I recommend that if you want to play chemist, you learn some chemistry, if only for the sake of safe practices.
 
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