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Personally I don't think it is fair to say that an aggressor in a situation must be the one who instigates physical confrontation. If Alice blocks Bob's path and verbally threatens him, instructing him to do follow her into an alley or she will attack him a strong argument could be made in defence of Bob striking first. The nature of his strike will later be called into question for if it was A) a reasonable decision based on the threat and B) a reasonable response to the threat in question.
Also members may want to review my post above in which the affidavit of two investigators claims that the screams heard in the back ground of various calls to the police (available here) are that of Trayvon Martin shouting for help.