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Biophysics problem - amino acid dipoles

  1. Jan 30, 2008 #1
    1. The dipole moment of a peptide bond is 3.7 Debye in water. Assuming that a hydrogen bond is essentially a dipole-dipole interaction, estimate the energy of a hydrogen bond between two peptides in water and in the interior of a protein (neglect the competing interactions with the solvent).

    2. Relevant equations
    [tex]_{}V_d_d = -2\left|\mu\right|^{}^2/D\left|r\right|^{}^3[/tex]

    3. The Debye part really confuses me. I tried plugging in 0.5 for the r value and using 1.23*10^-29 for the mu value. The D values are given as [tex]78.5\kappa\epsilon_{}_0[/tex] for water and [tex]3.5\kappa\epsilon_{}_0[/tex] for the interior of the protein. I feel like I'm almost there, but I don't quite have it. Please help! Thanks!
    1. The problem statement, all variables and given/known data

    2. Relevant equations

    3. The attempt at a solution
  2. jcsd
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