Biopolymer in tissue engineering

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Discussion Overview

The discussion centers on the use of biopolymers in tissue engineering, specifically focusing on polylactic acid (PLA) and its preparation for implantation. Participants explore the chemical and biological interactions of these materials, as well as their application in tissue repair.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested
  • Homework-related

Main Points Raised

  • One participant seeks information on how to prepare biopolymers like PLA for tissue repair and how to make them reactive to promote cell proliferation.
  • Another participant suggests conducting a literature search, noting that biopolymers have been studied extensively, particularly in the context of scaffolds for ligament repair.
  • A participant mentions that they found many articles but not specific information on the preparation steps discussed by their professor, such as adding proteins to create DNA and adhesive materials.
  • One participant provides a reference to a study involving bioglass filled polymer (PLA/PGA) that encourages device integration and offers antimicrobial properties.
  • There is uncertainty about whether the original poster is looking for the chemistry of polymer preparation or their biological interactions, leading to a suggestion to potentially move the discussion to a chemistry forum for more targeted assistance.
  • The original poster expresses a desire to understand how to prepare the polymer and the types of polymers used, agreeing that moving the thread to chemistry may be beneficial.

Areas of Agreement / Disagreement

Participants do not appear to reach a consensus on the specific information needed regarding biopolymer preparation and application. Multiple competing views and areas of uncertainty remain regarding the chemistry and biological interactions of the polymers.

Contextual Notes

Participants express limitations in their understanding of the specific preparation methods and the types of biopolymers used in tissue engineering, indicating a need for more detailed information that has not been fully addressed in the existing literature.

BME.rony
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hi every one
I am looking for any information about biopolymer used in tissue repairing
Like polylactic acid and how to prepare it for implantation?
How to make it reactive to become able to proliferation?


Can anyone help me please
I am really really desperate
 
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Have you attempted a literature search yet? There should be tons of articles on this topic considering these are subjects that have been studied AT LEAST since I was a grad student (one of my friends was working on biopolymers as scaffolds for ligament repair).

If you haven't done so yet, do a search at Pubmed for your topic.
http://www.ncbi.nlm.nih.gov/sites/entrez?dr=abstract

Is this for a paper for a class?
 
thanks for your help
You are right
I found a lot of articles on this topic but not what I am looking for
I am looking for the polymer itself
The professor talked about the steps for making the polymer suitable for tissue repairing
Like add a protein to produce DNA and adhesive material
I can't find any thing talk about that
 
I'm not entirely clear on what you're asking for (this is well outside my own area of expertise). Are you trying to understand the chemistry of how to prepare the polymers, or are you trying to find something on how the polymers work with biological tissues...or both? I realize this is a field that bridges both biology and chemistry as well as engineering fields (my friend who did this research was a biomedical engineer, but did much of her research within a chemistry department). So, I'm asking partly to help clarify the problem so we might get others to help more, and partly to determine if you might get more helpful responses in the chemistry forum rather than biology forum (if so, I can move this thread to chemistry). If moved, I'll leave a permanent redirect so it continues to get the attention of biologists as well.
 
Moonbear said:
I'm not entirely clear on what you're asking for (this is well outside my own area of expertise). Are you trying to understand the chemistry of how to prepare the polymers, or are you trying to find something on how the polymers work with biological tissues...or both? I realize this is a field that bridges both biology and chemistry as well as engineering fields (my friend who did this research was a biomedical engineer, but did much of her research within a chemistry department). So, I'm asking partly to help clarify the problem so we might get others to help more, and partly to determine if you might get more helpful responses in the chemistry forum rather than biology forum (if so, I can move this thread to chemistry). If moved, I'll leave a permanent redirect so it continues to get the attention of biologists as well.


I am looking for how to prepare the polymer and kind of polymer used
I think you are right it is beter to move it to to chemistry


thanks for your help
 
chemisttree said:
Here is one example of using bioglass filled polymer (PLA/PGA) to both encourage the integration of the device and provide an antimicrobial prophylaxis.

thanks but I could not find what i am looking for
 

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