Yes; but the buffering is not inherently stable - probably from the age of 50 onwards (or whenever it becomes unstable).
Bicarbonate is produced by the kidneys as a buffer against excess acidity in the blood, and is capable of performing this task until the kidneys decline in function (and then a mild case of metabolic acidosis, or excess acidity that is nonlethal, ensues)
https://examine.com/supplements/sodium-bicarbonate/ (1.2. Biosynthesis and Regulation)
Do understand ... I don't rate myself as being fully up to speed on this subject.
However, I am reasonably proficient at gaining a rapid overview, by resorting to credible published literature, and gaining the key points.
If I intend to delve deeper then a folder is allotted, and the bookmarks fill up.
In this case, it quickly became apparent that acidosis is, or can be, a fact of life.
... and that ingestion of sodium bicarbonate (or restriction), does impact blood pH.
In terms of tumours ... current thinking is that they prefer a more acidic environment, and that a balanced pH is less to their liking.
From this, for people of a certain age, there may be reason to consider supplementing sodium bicarbonate production.
... particularly in instances where tumours and cancer cells are present.
Certainly, for anyone in this group, there is enough evidence to carry out further investigation.
From a general 'chemical productivity' perspective - there is no serious dispute over the assertion that our productivity drops (pretty much across the board) with age.
... and that 'chemical importation' is a valid strategy for maintaining a healthy system.
There is also a continually growing body of evidence, that boosting certain naturally produced (or normally ingested) elements, can have a positive impact on health.
(RDA +).
Within the practicing medical profession, as a general principal ... this is understood.
A fact that is easily confirmed, by asking for their opinion.
The problem they have, is that there is a lack of 'protocols' ... and either way 'this is not their field of study'.
Consequently, their opinion is positive, but no more than that.
At best, a statement of 'no contraindications' will be forthcoming (if such is the case).
... but my guess is that such conversations are rarely (or never) initiated by the medical practitioner.
Hand over a list ... it will be (should be) looked over, and handed back with positive mumblings.
IE. Not kept on file.
I quickly learned that it is entirely unfair to expect them to become involved, when their hospital services don't include a specialist that they can refer you to.
Think of it like an official car dealer - they repair the car according to their protocols.
You can modify your car, if you want, and improve it.
... but if you don't know what you are doing, you can create other problems.
Eg. An increase in sodium bicarbonate could cause a decrease in potassium.
increased sodium excretion further results in increased potassium excretion. As sodium is ingested via sodium bicarbonate but potassium is not, chronic and excessive usage of sodium bicarbonate supplementation is a potential risk factor for reducing serum potassium concentrations.
https://examine.com/supplements/sodium-bicarbonate/ (11.2. Cations Sodium and Potassium)
Either way, there is clearly a lag between the medical research, and the growth in medical practitioners (in this field).
Fine if you are careful, and follow the credible advice that is available from the few specialists that do exist.
However, there is a great deal of information that is shoddily produced.
My belief was that the 'honey - sodium bicarbonate protocol' was false information.
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Regarding published studies concerning this general subject - here is another that sprung up:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736774/
