The quarks don't have well-defined positions inside the nucleons, there are no "arrangements" that could change.
Not even the total number of quarks (valence plus sea quarks) is a well-defined quantity.
Are you asking whether quarks move between one nucleon and another, or are you asking whether they change their arrangement within one nucleon? It's not obvious to me whether the former is a well-defined question, since they're identical particles.