Can we receive monozygotic (identical) twins in apes?

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SUMMARY

The discussion centers on the feasibility of creating monozygotic (identical) twins in apes, specifically chimpanzees and bonobos, through in vitro fertilization (IVF) techniques. The proposed method involves fertilizing an egg cell, creating a zygote, and then splitting the morula into two independent morulas for implantation. Additionally, the use of hormones such as PZP (porcine zona pellucida), which has been effective in inducing twinning in sheep, is suggested as a potential method for achieving identical twins in apes. However, the applicability of these techniques to chimpanzees and bonobos remains uncertain.

PREREQUISITES
  • Understanding of in vitro fertilization (IVF) techniques
  • Knowledge of embryonic development stages, particularly morula formation
  • Familiarity with hormonal influences on reproduction in animals
  • Basic concepts of animal genetics and twinning
NEXT STEPS
  • Research the application of PZP hormone in animal reproduction
  • Explore advanced IVF techniques used in primate species
  • Investigate the ethical considerations of genetic manipulation in apes
  • Consult scientific literature on successful twinning methods in other mammals
USEFUL FOR

Researchers in animal reproduction, veterinarians specializing in primate care, and geneticists interested in cloning and twinning techniques will benefit from this discussion.

Eagle9
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Hello again :oldsmile:

Let’s assume that for some scientific reasons we need to have monozygotic (identical) twins in apes, for example in chimpanzee or bonobo.

So I take egg-cell from female, fertilize it with spermatozoon and receive zygote and it (more precisely morula) later can be implanted in female, an ordinary In vitro fertilization (but in animals) actually.

But before implanting I can cut morula in two (or more) pieces very carefully. Each part now is independent morula, both parts contain only undifferentiated cells and I can implant both of them in female and it will give birth to identical twins, this can be done?

Or perhaps there is another way? Can we give some chemical substance (hormone maybe?) to female ape just after/before female has sex with male ape? Can such substance in principle cause the zygote/morula to divide in two parts/twins? :oldeyes:
 
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That's an interesting question! I'm not sure if it's possible to create monozygotic twins in apes through the methods you mentioned, but I do know that it is possible for other animals like sheep. There are certain hormones and proteins that can be used to induce twinning in animals. For example, a hormone called PZP (porcine zona pellucida) has been used with some success to induce twinning in sheep. However, I'm not sure if the same process would work in chimpanzees or bonobos. You might want to do some more research on the subject or consult with a veterinarian or scientist who specializes in animal reproduction.
 

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