Canine transmissible venereal tumour - CTVT

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A contagious canine cancer known as transmissible venereal tumor (CTVT) has been traced back approximately 6,000 years to Asia, spreading globally through dog mating practices. This unique cancer transmits living cancer cells between dogs, primarily resulting in genital tumors. CTVT is notable for being the oldest and most prolific cancer lineage identified in nature, having originated from a single dog and persisting beyond its death through transmission to new hosts. The discussion also touches on similar cancers in other species, such as a cancer affecting Tasmanian devils, which spreads through biting, highlighting the intriguing ways cancers can evolve and propagate across different species.
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https://www.wired.com/story/how-a-6000-year-old-dog-cancer-spread-around-the-world/
How a 6,000-Year-Old Dog Cancer Spread Around the World
A massive collection of dog tumor samples is revealing the secrets of a contagious, parasite-like cancer that could help explain human cancers too.https://www.cam.ac.uk/stories/canine-cancer
The curious tale of the cancer ‘parasite’ that sailed the seas

A contagious canine cancer conquered the world by spreading between dogs during mating. Scientists believe it arose around 6,000 years ago in Asia and spread around the globe through maritime activities.

Canine transmissible venereal tumour’ is a cancer that spreads between dogs through the transfer of living cancer cells, primarily during mating. The disease usually manifests as genital tumours in both male and female domestic dogs. It first arose in an individual dog, but survived beyond the death of the original dog by spreading to new dogs. The cancer is now found in dog populations worldwide, and is the oldest and most prolific cancer lineage known in nature.
I've had dogs and cats, and while I've heard of various viruses (e.g., parvo, . . . ) and cancers, I've never heard of CTVT before until now.

The Wired article has a discussion of a cancer spread by clams and mussels of which I was not aware.
 
Biology news on Phys.org
There is also a similar cancer of Tasmanian Devils.
It grows on their faces and is spread by cell transfer when they bite each others faces (something Tasmanian devils do a lot of apparently).
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
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