Do diabetics have sugary interstitial fluid?

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SUMMARY

Diabetics experience elevated glucose levels in their interstitial fluid due to the leakage of blood plasma from capillaries, especially when insulin is absent or ineffective. In Type 1 diabetes, the lack of insulin prevents glucose from entering cells, resulting in high interstitial fluid glucose concentrations. Continuous Glucose Monitors (CGMs) can measure glucose levels in interstitial fluid, reflecting blood glucose levels with a time lag of approximately 10 minutes. Therefore, when blood sugar is high, interstitial fluid sugar concentration is also elevated.

PREREQUISITES
  • Understanding of diabetes types: Type 1 and Type 2 diabetes
  • Knowledge of glucose metabolism and insulin function
  • Familiarity with Continuous Glucose Monitors (CGMs)
  • Basic principles of capillary function and diffusion
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  • Research the mechanisms of glucose transport in diabetic patients
  • Learn about the physiological differences between Type 1 and Type 2 diabetes
  • Explore the technology and accuracy of Continuous Glucose Monitors (CGMs)
  • Investigate the effects of insulin therapy on interstitial fluid glucose levels
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Individuals with diabetes, healthcare professionals, researchers in endocrinology, and anyone interested in the physiological effects of glucose on the body.

Lo.Lee.Ta.
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So my understanding is that capillaries leak out their blood plasma containing sugar and other nutrients insulin (when sugar present)near body cells, and this is what comprises interstitial fluid.
But what if no insulin is present (Type 1 diabetes) or insulin creates no response (Type 2 diabetes)?
Does the interstitial fluid just remain sugary since the glucose can't enter the cells?
My understanding is that capillaries only use diffusion as transport, so they can't reabsorb glucose from the interstitial fluid, right?
When someone has a "high blood sugar," does this also mean that interstitial fluid sugar concentration is also high...?

Thanks SO much! :)
I have been researching this forever but can't find a clear answer! #=_=
 
Any answer?, i want to know too.
 
Continues Glucose Monitors (CGM) used in people with diabetes to track their blood glucose levels every 5 minutes or so can be used to check their blood glucose from the interstitial fluid, obviously there is a time-lag between the blood that is directly from plasma and the interstitial fluid, of about 10 minutes. So to answer the question, yes interstitial fluid would contain high glucose if a person is diabetic and didn't main their glucose levels with insulin (Mainly T1) and (Oral Meds T2).

Blood flow rich in glucose from capillaries would leak into the interstitial fluid, when their glucose plasma is high, it will also mean their interstitial fluid is high in glucose too.
 
Thank you Kiyal,
 

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