Does an unicellular organism die..... if it does not get nutrient substancees for a long time? What I mean by death is that it does not replicate it's dna, trancribe gene and translate them to protein, carry out metabolic processes as it normally does, even when there are surplus nutrient elements. If the answer is yes. Then the next question is: why? It is understandable that without nutrient it cannot carry out many vital processes..... In this case it cannot carry out them for a long interval. But after that interval it has access to nutrient.... but it cannot manipulate them to continue life as it did before. What happened in this period (of drought) that has irreversibly shifted it to a position from which it cannot come back to manifest life? How this shift (shift away from life) takes place?