^
I reckon G01 thought that the "nearly all who try fail" comment was directed at people who have already entered grad programs? Well, that's what I thought anyway!
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OP, if you have a broad interest in the sciences (and it seems so; why else would you not take further maths and additional further maths instead of chem and bio?), you shouldn't restrain yourself to one subject now, let alone, one specific sub-field of that subject! Your interests can change.
You may find that you really dig systems biology or climate science, and then do grad work there instead! Or that you just don't like uni-level physics, and go find a job instead. Or maybe you end up really liking philosophy of science.
Right now, assuming you want to stay in the UK, the best thing to do is get the best grades you can. As far as I'm aware, that's all that's required to get into a "top uni" in the UK. Excluding Oxbridge, of course, where one would have interviews.