How Well Is the Human Interferon Pathway Understood in the Immune System?

[Fra]

How well is the human interferon pathways and exact function in the immune system known, and how well is the and regulatory system from gene to protein level known?

If anyone has any pointers to reviews of the interferons in the contact of immune system and in particular what regulates it naturally (assuming it's not given as drugs).

/Fredrik

 

[Fra]

It seems p53 induction is thought to be one key point in the context of cancer suppression.

Used as a cancer-drug, is p53 induction the presume only point, or are there additional points of the interferon?

/Fredrik