Yes, in a trivial way. Just define [itex]\mu(S)=0[/itex] for all S. Or take the counting measure. Or a point measure.
A better answer is actually Riesz representation theorem. This says that all regular measures on a locally compact Hausdorff space coincide with positive functionals
[tex]T:C_c(X)\rightarrow \mathbb{R}[/tex]
(with [itex]C_c(X)[/itex] the functions to [itex]\mathbb{R}[/itex] with compact support). Such a functional exist because of the Hahn-Banach theorem.
The same thing can be done with [itex]C_0(X)[/itex] actually. In that case: the measures are the positive functionals, the probability measures are the states and the point measures represent the pure states on X.
In general, the existence of non-trivial measures is not a simple problem and requires set theory (see for example measurable cardinals)