- #1
- 5,661
- 4,504
From: https://www.cell.com/med/fulltext/S2666-6340(21)00153-7?utm_source=EA
Blood oxygenation through the lower intestinal tract is demonstrated in both mice and pigs. It is hoped this wiil work for those Humans that need temporary assistance with respiratory function.
Inspired by organisms such as loaches that use intestinal air breathing, we show the effectiveness of an enteral ventilation approach in attaining systemic oxygenation in both rodent and porcine models. Intra-rectal delivery of a liquid form of O2 known as conjugated perfluorocarbon, a compound historically used in clinics for liquid ventilation through airway administration, is highly tolerable and efficacious in ameliorating severe respiratory failure.
Blood oxygenation through the lower intestinal tract is demonstrated in both mice and pigs. It is hoped this wiil work for those Humans that need temporary assistance with respiratory function.
Inspired by organisms such as loaches that use intestinal air breathing, we show the effectiveness of an enteral ventilation approach in attaining systemic oxygenation in both rodent and porcine models. Intra-rectal delivery of a liquid form of O2 known as conjugated perfluorocarbon, a compound historically used in clinics for liquid ventilation through airway administration, is highly tolerable and efficacious in ameliorating severe respiratory failure.
