Measuring Voltage Across the Blood-Brain Barrier: Is the Dermis a Barrier?

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Is there a way to measure the amount of voltage used when transmitting from the blood brain barrier to a particular muscle outside of the skin or is the dermis too thick?
 
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Hmm, I am by no means knowledgeable in matters of biology, but it seems to me you are somewhat confused about at least the terminology, if not the functionality.
The blood-brain barrier has no direct relation to nerve signal transmission. Its function is to essentially be a screen for molecules that have no business being in the brain.
The dermis is just a fancy name for skin. It also has nothing to do with receiving muscle signals; those signals, as should be probably obvious, terminate in the muscle they are supposed to actuate.

Now, if your *actual* question is "how can you measure the voltage difference between the brain origin of the signal, and its terminus in the muscle, the simple answer is: electrodes.

If the question is, can you detect a nerve signal from outside the body, there's a lot of variables involved. Maybe a question better asked in a biology forum.
 
I wish to measure the voltage terminating at the muscle from outside the skin.
 
I've moved this to the biology forum from General Physics, as it seems like it may require more assistance from our biology-knowledgeable members.