Measuring Voltage Across the Blood-Brain Barrier: Is the Dermis a Barrier?

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Discussion Overview

The discussion centers around the feasibility of measuring voltage related to nerve signal transmission from the blood-brain barrier to muscles, particularly considering the role of the dermis as a potential barrier in this measurement process. The scope includes aspects of biology and physiology as they relate to electrical signals in the body.

Discussion Character

  • Exploratory, Debate/contested, Conceptual clarification

Main Points Raised

  • One participant questions the terminology and functionality related to the blood-brain barrier and nerve signal transmission, suggesting a misunderstanding of the concepts involved.
  • Another participant clarifies that the blood-brain barrier functions to screen molecules rather than directly relate to nerve signal transmission.
  • A suggestion is made that electrodes could be used to measure the voltage difference between the brain and the muscle, although this is contingent on various factors.
  • There is a specific inquiry about whether the measurement can be made in contact with the skin or not.
  • The thread has been moved to a biology forum for further discussion, indicating a belief that the topic may require more specialized knowledge.

Areas of Agreement / Disagreement

Participants express differing views on the relationship between the blood-brain barrier and nerve signal transmission, indicating a lack of consensus on the terminology and concepts involved. The discussion remains unresolved regarding the practical aspects of measuring voltage in this context.

Contextual Notes

There are limitations regarding the assumptions about the relationship between the blood-brain barrier and nerve signals, as well as the variables involved in measuring voltage from outside the body.

thisguy
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Is there a way to measure the amount of voltage used when transmitting from the blood brain barrier to a particular muscle outside of the skin or is the dermis too thick?
 
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thanks in advance for your input.
 
Hmm, I am by no means knowledgeable in matters of biology, but it seems to me you are somewhat confused about at least the terminology, if not the functionality.
The blood-brain barrier has no direct relation to nerve signal transmission. Its function is to essentially be a screen for molecules that have no business being in the brain.
The dermis is just a fancy name for skin. It also has nothing to do with receiving muscle signals; those signals, as should be probably obvious, terminate in the muscle they are supposed to actuate.

Now, if your *actual* question is "how can you measure the voltage difference between the brain origin of the signal, and its terminus in the muscle, the simple answer is: electrodes.

If the question is, can you detect a nerve signal from outside the body, there's a lot of variables involved. Maybe a question better asked in a biology forum.
 
I wish to measure the voltage terminating at the muscle from outside the skin.
 
In contact with the skin, or not?
 
I've moved this to the biology forum from General Physics, as it seems like it may require more assistance from our biology-knowledgeable members.
 

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