Meta Analysis with Several Regression Studies

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SUMMARY

This discussion centers on synthesizing multiple regression studies to model a response variable z_1 as a function of predictor variables x_1 and y_1. The user references four studies: Study 1 presents a regression model for z_1, Study 2 for z_2, Study 3 establishes a correlation between z_1 and z_2, and Study 4 between x_1 and y_1. The user seeks resources on multivariate least squares regression and total least squares regression, specifically regarding the treatment of z-variables and x-variables as random variables.

PREREQUISITES
  • Understanding of multivariate least squares regression
  • Familiarity with total least squares regression
  • Knowledge of covariance estimation between variables
  • Experience with regression model synthesis techniques
NEXT STEPS
  • Research comprehensive texts on multivariate regression analysis
  • Explore resources on total least squares regression methodologies
  • Learn about covariance estimation techniques for multiple variables
  • Investigate methods for synthesizing regression models from multiple studies
USEFUL FOR

Statisticians, data analysts, and researchers involved in regression analysis and model synthesis, particularly those working with multivariate data sets.

quantumdude
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I have come across a problem that I need to solve, and it isn't your garden variety regression problem. It isn't even covered in any of my books, of which I have many. I need either a book title or an online PDF that covers this material.

Suppose we have a response variable z_1 that depends on predictor variables x_1,x_2,...,x_n. Further suppose that we have another response variable z_2 that depends on predictor variables y_1,y_2,...,y_m.

There are 4 studies to be synthesized.

In Study 1 a regression model z_1=\alpha_0+\alpha_1x_1+\alpha_2x_2+...+\alpha_nx_n is obtained.
In Study 2 a regression model z_2=\beta_0+\beta_1y_1+\beta_2y_2+...+\beta_my_m is obtained.
In Study 3 a correlation between z_1 and z_2 is obtained.
In Study 4 a correlation between x_1 and y_1 is obtained.

The goal is to synthesize these studies to model z_1 as a function of x_1 and y_1 only.

What's a good read to get going on this? Thanks!
 
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Are these regression models fit by considering both the z-variable and x-variables to be random variables? (e.g. total least squares regression as opposed to least squares regression?)

Are x1 and y1 the only random variables with a given estimated covariance ? - or do all pairs xj, yj have an estimate covariance?
 
Hi Stephen, thanks for replying.

Stephen Tashi said:
Are these regression models fit by considering both the z-variable and x-variables to be random variables? (e.g. total least squares regression as opposed to least squares regression?)

I'm dealing with multivariate least squares regression models.

Are x1 and y1 the only random variables with a given estimated covariance ? - or do all pairs xj, yj have an estimate covariance?

It's just the one pair of predictor variables for which I have an estimated covariance. But leaving that aside, what I really want to know is if there is a comprehensive reference from which I could learn how to combine regression models. It would be a bonus if both cases in your question were covered. Thanks!
 

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