I Nuclear knockout reactions - why does a proton knockout a neutron?

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The discussion centers on the proton knockout reaction in the synthesis of F-18 for FDG, specifically why a neutron is ejected instead of another proton during the collision of O-18 with an accelerated proton. The reaction is not a 50/50 chance; rather, the dynamics of nuclear forces favor neutron ejection. Additionally, when F-18 is formed, it initially carries a positive charge but quickly becomes an anion by capturing an electron from the environment, which helps balance the charge in the solution. The process of bombarding oxygen with protons can lead to various reactions, but the focus is on the desired formation of fluorine. Overall, the equipment's grounding maintains neutrality despite the presence of positive charges from the proton beam.
skh149
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Questions about the formation of F-18 from O-18; why a neutron is selectively knocked out, how do the charges balance out
I am studying the synthesis of FDG for a job interview. The process of creating the F-18 used in FDG involves the collision of O-18 with an accelerated proton -- the proton kicks out a neutron and everything adds up. I am just wondering why a neutron is specifically knocked out, why wouldn't another proton be kicked out instead? Is it 50/50 but the proton exchange is essentially no change at all? Thanks for any replies.

Bonus question: I might make this a separate post. But when the F-18 is formed it would be positively charged. I believe it quickly turns into an anion but still, the charges would not be balanced in the system (correct?). Would the solution have an overall electrical charge? Are electrons stripped from the environment? (In chemistry you usually can't just add a charged particle to a solution without its opposite charge. I.e. Na+Cl- )
 
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O-18 + p -> O-18 + p is a possible (and even likely) reaction, it's just not the reaction people are interested in. You can't control what reaction happens but you can bombard oxygen (or water) with enough protons and then separate out fluorine.

It's an ion briefly but it will quickly capture a random electron from the environment.
Your proton beam is a source of positive charges but grounding the equipment keeps it neutral.
 
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