What triggers the onset of labor in pregnancy?

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SUMMARY

The discussion centers on the biological triggers of labor onset in pregnancy, highlighting the uncertainty surrounding the exact mechanisms involved. Participants note that while labor can be induced using prostaglandins and oxytocin (Pitocin), the natural signals prompting these hormonal releases remain unclear. Theories suggest that labor initiation may result from a combination of fetal, maternal, and placental factors, rather than a single trigger. The conversation also touches on the influence of stress and the "nesting instinct" on labor timing.

PREREQUISITES
  • Understanding of hormonal roles in pregnancy, specifically prostaglandins and oxytocin.
  • Knowledge of fetal development stages and maternal physiological changes.
  • Familiarity with the concept of stress and its effects on pregnancy outcomes.
  • Awareness of terms like pre-eclampsia and hypertension related to pregnancy.
NEXT STEPS
  • Research the role of prostaglandins and oxytocin in labor induction.
  • Explore current studies on fetal and maternal signaling mechanisms during labor onset.
  • Investigate the psychological impact of stress on pregnancy and labor timing.
  • Learn about the nesting instinct and its correlation with labor initiation.
USEFUL FOR

Expectant parents, obstetricians, midwives, and researchers interested in the biological and psychological factors influencing labor onset.

Kerrie
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Moonbear, hope you read this one...

I am due to have my baby in just a little under 5 weeks. Although childbirth isn't a new experience for me (at least in the last 6 years), I truly wonder what triggers labor. Is it something in the brain? Any insight (in simple terms please!) would be good to know. I am well aware of all of the little physical signs that "things are happening", but I want to know a little more on the biological aspect of it.
 
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Kerrie, yours is the million dollar question! We really don't know. Some say it's a factor produced by the fetus, others say it's something in the mother, yet others suggest it's something produced by the placenta, but they're all still guessing.

In other words, sure, we know we can induce labor with prostaglandins and oxytocin (Pitocin), but we don't know what normally provides the signal for those hormones to be released for labor to begin. Since we do know we can induce labor if necessary, the biggest reason for wanting to identify this signal is to prevent premature labor, or even be able to test for something to predict if someone is at risk for it.

My intuition says it's not going to be a single "trigger" but that it's the outcome of a gradual process that's occurring throughout that last month of pregnancy (as you're well aware, you start getting those Braxton-Hicks contractions and other signs and symptoms that your body is getting ready to go into labor over the course of several weeks). This is probably why it's so hard to pinpoint and understand, because it's probably a long progression of events rather than one single event.

I really wish I did have a good answer. I'll look later to see what the most current research says and if there is any consensus yet whether it's more likely a fetal or maternal signal or a combination of both.
 
thanks moonbear :smile:

looking forward to reading what you find...
 
ohhhh 5 weeks left! I'm getting excited for you and hope everything is just perfect.
I find its weird that we don't know what causes labor to begin. One of my sisters was due to have a child, she went past her due date and we became concerned. Then she told us, SHE was not ready, the babies room was not done, and she was really stressed with some other issues.
Once she finnished the room, and was able to relax unhindered a few days, the baby came. From that time on I always thought that the baby knew how stressed she was, and just waited for mom to relax.
 
Last edited:
Interesting hypatia, I have told myself that I want the baby to arrive after school starts (sept 12), which is certainly well before her due date, but judging by my last time, I was two weeks early.
 
hypatia said:
ohhhh 5 weeks left! I'm getting excited for you and hope everything is just perfect.
I find its weird that we don't know what causes labor to begin. One of my sisters was due to have a child, she went past her due date and we became concerned. Then she told us, SHE was not ready, the babies room was not done, and she was really stressed with some other issues.
Once she finnished the room, and was able to relax unhindered a few days, the baby came. From that time on I always thought that the baby knew how stressed she was, and just waited for mom to relax.

Funny, everyone else I know who didn't end up being induced or having a c-section scheduled has gone into labor while right in the middle of some major project. I attributed it to that nesting instinct that seems to make women decide it's time to redecorate, or repaint garage doors, or install new flooring in the living room only a few weeks before they are due. But, then again, it doesn't seem to stress out the women, but their husbands who are the ones who have to do most of the work and are suddenly left with this big project to finish as their wife is going into labor. :biggrin:

Kerrie, I haven't had a chance to look up anything yet.
 
I have been definitely having that "nesting" instinct going on...my place sparkles! Last weekend I had the urge to completely go through my kids' room (baby will have to share with them for the time being) and clean out all of the small objects that little ones like to put in their mouth. After a few hours of that, I was exhausted, but was frustrated I couldn't complete it.
 
Pardon me for being ignorant, but I haven't had any children yet. Doesn't large amounts of stress during the pregnancy increase the risk of high blood pressure (can't remember the name. Its right on the tip of my tongue!) and premature labour?

~Kitty
 
misskitty said:
the risk of high blood pressure (can't remember the name. Its right on the tip of my tongue!)
Hypertension?
 
  • #10
pre-eclampsia
 
  • #11
Pre-eclampsia was it. :biggrin: Thanks Monique. So back to the original query.

~Kitty
 

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