PKa values for weak/strong bases

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SUMMARY

The discussion clarifies the distinction between weak and strong acids and bases based on pKa and pKb values. A pKa value below 1 typically indicates a strong acid, while a value above 3 suggests a weak acid; however, this classification is not absolute and can vary depending on the solvent used. In liquid ammonia, for example, substances stronger than acetic acid are considered strong, demonstrating the levelling effect of solvents on acid-base strength. The conversation emphasizes the importance of solvation effects and the context in which acids and bases are evaluated.

PREREQUISITES
  • Understanding of pKa and pKb values in acid-base chemistry
  • Familiarity with solvation effects in different solvents
  • Knowledge of acid-base dissociation in aqueous and non-aqueous environments
  • Basic concepts of proton donation and acceptance
NEXT STEPS
  • Research the levelling effect of solvents on acid-base strength
  • Study the behavior of acids and bases in non-aqueous solvents
  • Explore the concept of solvation and its impact on pKa values
  • Learn about the differences in acid strength in gas phase versus liquid phase
USEFUL FOR

Chemistry students, researchers in acid-base chemistry, and professionals working with solvents in chemical reactions will benefit from this discussion.

kasse
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In chemistry it's normal to distinguish between weak and strong acids. Is there a limit for the pKa value that determines what is strong and what is weak?

Equivalent, for bases, is there a pKb value that separates weak and strong bases?
 
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As a first approximation you may assume that everything with pKa<1 is strong, and everything with pKa>3 is weak (symmetrically for bases). Between 1 and 3 is a grey area. But if now someone will answer telling you that strong is below 0 and weak is above 2 - s/he will be right as well. There is no set limit, as these things tend to be somewhat relative.
 
And of course we mostly think in terms of water solvent. But in liquid ammonia solvent anything stronger than acetic acid is 'strong' and fully dissociated, while in acetic acid solvent HCl and HNO3 are fully associated and perchloric acid is one of the few remaining dissociated, so 'strong'. This is called a 'levelling' effect.

It depends on solvation effects and (not always) oproton donation to /acceptance from the medium.
These effects are absent in the gas phase where all molecules are extremely weak acids. But there e.g. the water molecule is a weaker acid (proton donor) than toluene!
You will mostly deal with water medium but just a little relativisation. :cool:
 

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