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Primary Amebic Meningoencephalitis

  1. Dec 9, 2005 #1
    Anyone here familiar with this topic? If so, have you done any research relating to the infection and the mortality rates resulting from it. I am curious as to the possibility of this infection becoming more pronounced with the advent of global warming, since the cause of it is a small thermphilic amoeba. PAM (Primary Amebic Meningoencephalitis) is usually 100% fatal. However there have been four or maybe five reported cases of the host having survived this often fatal infection. I am also curious as to how many cases there have been which were misdiagnosed due to the infection appearing as a bacterial infection rather than amebic, which most often occurs and is not realized until after autopsy of the infected and then deceased host.
    The cause of the infection is the introduction of the amoeba Naegleria fowleri into the nasal cavity during swimming or diving into warm fresh natural waters, where it then travels via the CNS (Central Nervous System) to the brain. Of course there it begins to propogate and cause sever bleeding, destruction of brain cell tissues and of course swelling leading to the death of the host. The amoeba can also thrive in most any warm body of freshwater including poorly treated swimming pools.
    In any case I would enjoy hearing what others may have to say on this infection and what light they may have to shed on what I have not or may have already researched. Thanks:smile:
  2. jcsd
  3. Dec 9, 2005 #2


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    Primary Amebic Meningoencephalitis -- North Carolina, 1991

    Primary Amebic Meningoencephalitis --- Georgia, 2002

    Emerging Infectious Diseases
    Fatal Naegleria fowleri Meningoencephalitis, Italy

    CDC also does - Surveillance for Waterborne-Disease Outbreaks
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