Psychopaths have Bigger Striatum area in Brain

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The striatum plays a crucial role in various cognitive functions, including motor planning, decision-making, motivation, and reward perception. Research indicates that individuals with psychopathic traits possess a striatum that is approximately 10% larger than that of non-psychopaths, highlighting a biological difference. Psychopathy is characterized by egotism, antisocial behavior, lack of guilt, and empathy, often linked to criminal tendencies. However, the classification of psychopathy as a mental health disorder is contentious, as it primarily serves to label criminal behavior rather than being formally recognized as a disorder. Critiques of neuroscience research on psychopathy suggest that many studies lack consistency and clarity, often oversimplifying complex behaviors into biological abnormalities. This ongoing debate emphasizes the need for a nuanced understanding of the interplay between brain structure and behavior, rather than relying on simplistic cause-and-effect explanations.
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The striatum... coordinates numerous elements of cognition, including motor and action planning, decision-making, motivation, reinforcement, and reward perception.
Psychopaths, or those with psychopathic qualities, are people who have an egotistical and antisocial disposition. This is often characterized by a lack of guilt for their actions, a lack of empathy for others, and, in some cases, criminal tendencies.
...psychopathic people have a 10% larger striatum, a cluster of neurons in the subcortical basal ganglia of the forebrain, than regular people. This represents a clear biological distinction between psychopaths and non-psychopathic people.

Popular article:
https://scitechdaily.com/scientists...erence-between-psychopaths-and-normal-people/

Research article (paywall):
https://dx.doi.org/10.1016/j.jpsychires.2022.03.006

Cheers,
Tom
 
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I have to say, whenever I see things like this, specifically related to psychopathy, it brings into focus why such a large amount of published work in neuroscience is labelled as neurotrash. Its obviously true that there is a small group of people, whose behaviour is so extreme and damaging, that they attract a great deal of public attention. This means that exploiting the known links between brain and behaviour, provides an attractive explanation, that this is caused by a biological abnormality, it makes such behaviours understandable and reduces anxiety.

Unfortunately, such explanations are really just simplistic fictions, the good research that is available finds little consistency in findings in the results from the whole range of areas of study. These findings, not being helped by the lack of clear definitions, poor measurement tools and in some cases the motives of researchers.

Despite the influence this idea has, it is worth recognising that psychopathy is not formally recognised as a mental health disorder, its primary function is in the labelling of criminal behaviour and in the justification of sentencing.

The two links discuss the problems of making sense of the research, it in many ways reinforces the view that we can only understand people by taking apart the complex web of associations that lead to particular outcomes, simple cause - effect associations are not as common as we like to think.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219694/
https://www.apa.org/monitor/2022/03/ce-corner-psychopathy
 
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https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...

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