Questions on synthesizing Fluorine 18

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SUMMARY

Fluorine-18 (F-18) is primarily produced for PET scans using an 11-18 MeV cyclotron by bombarding Oxygen-18 with protons. An alternative synthesis method involves the NEON-20(DEUTERON, ALPHA)FLUORINE-18 reaction, requiring only 1-3 MeV. However, producing F-18 via neutron bombardment is not feasible due to its neutron-poor nature. Additionally, creating a simple deuteron emitter, akin to the Americium-241 and Beryllium foil neutron source, is challenging due to the instability of deuterons and their low binding energy.

PREREQUISITES
  • Understanding of nuclear reactions, specifically positron emission and neutron bombardment.
  • Knowledge of cyclotron operation and particle acceleration techniques.
  • Familiarity with isotopes, particularly the properties of Fluorine-18 and Oxygen-18.
  • Basic principles of nuclear binding energy and stability of isotopes.
NEXT STEPS
  • Research the NEON-20(DEUTERON, ALPHA)FLUORINE-18 reaction in detail.
  • Explore advanced cyclotron techniques for ionizing deuterium gas.
  • Investigate alternative methods for producing neutron sources in nuclear applications.
  • Study the stability and decay processes of neutron-poor isotopes.
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Researchers in nuclear chemistry, medical physicists involved in PET scan technology, and professionals exploring alternative methods for isotope production.

Strat-O
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I have a couple questions but first some background:

Fluorine 18 is used in PET scans as a beta+ emitter. Generally it is created with an 11-18 MeV cyclotron by bombarding Oxygen 18 with protons. I read a paper that said there was an alternative way to produce F 18 by the NEON-20(DEUTERON, ALPHA)FLUORINE-18 reaction that only requires about 1-3 MeV. My question is, are there other ways that any of you know of to transmute a relatively stable isotope into F 18 by, say neutron bombardment?

Another question:
If you wrap Americium 241 with Beryllium foil you create a neutron source that gives off about 5 MeV neutrons. What's neat about that is it's all passive--nothing to plug in, it just works. Is there a way that you can create a Deuteron emitter that works just as simply?

Thanks!

Marlin
 
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Natural, stable F is 19F. 18F has one less neutron for that number of protons, which is why it decays by positron emission. Because it's on the neutron-poor side of the line of optimal stability, you really can't produce it by irradiating a target material with neutrons.

A deuteron is quite an unstable nucleus - it has relatively low binding energy per nucleon, which is why it likes to react with other light nuclei in reactions such as D-D and D-T fusion, for example.

Because it's relatively weakly bound, it's very unlikely to be found as the product of a nuclear reaction, analogous to the 9Be(alpha, n)12C reaction that goes on inside an alpha-Be neutron source.

To make a source of energetic deuterons, you ionise deuterium gas within the ion source of a particle accelerator such as a cyclotron, just as you would with unenriched hydrogen if you were using a proton beam.
 
Thank you Minerva. Looks like good info.

Marlin
 

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