Which Site Will Grignard Reagent Attack: Ketone or Alkene?

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SUMMARY

The discussion centers on the reactivity of Grignard reagents, specifically determining whether a Grignard reagent will attack a ketone or an alkene in a given reaction. Participants emphasize the importance of understanding the nucleophilic nature of Grignard reagents, which preferentially react with electrophiles such as ketones over alkenes due to their higher reactivity. The consensus is that Grignard reagents will attack the ketone, leading to the formation of an alcohol after subsequent hydrolysis. This conclusion is based on established principles of organic chemistry regarding nucleophilic addition reactions.

PREREQUISITES
  • Understanding of Grignard reagents and their properties
  • Knowledge of nucleophilic addition reactions
  • Familiarity with ketones and alkenes as functional groups
  • Basic principles of organic reaction mechanisms
NEXT STEPS
  • Study the mechanism of Grignard reagent reactions with ketones
  • Explore the differences in reactivity between ketones and alkenes
  • Learn about the hydrolysis of Grignard reagents to form alcohols
  • Investigate other nucleophiles and their reactivity with various electrophiles
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Chemistry students, organic chemists, and educators looking to deepen their understanding of Grignard reagents and their applications in organic synthesis.

Aryamaan Thakur
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TL;DR
What product will be formed when reacted with Phenylmagnesium Bromide if the competition is between a carbon-oxygen double bond and a carbon-carbon double bond(as shown in figure)?
This is the given reaction:https://www.physicsforums.com/attachments/1559750554233-png.244625/
244628


Where will the reaction take place - at ketone or at alkene? And why?
 
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This sounds like a homework problem. Please note that we don’t provide answers to homework problems here, and that you’re not likely to receive positive feedback unless you show at least an attempt at a solution.
 

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