Reactions, Organic and Medical Substances

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SUMMARY

The forum discussion centers on the chemical reactions involving various organic and medical substances, specifically focusing on the reactions of aromatic primary amines with p-DAB HCl, alcohols with diazo compounds, and ketones with various reagents. The user, a student at the Faculty of Medicine, University of Sriwijaya, seeks assistance in completing a chemistry lab report that includes multiple complex reactions. Key reagents mentioned include p-DAB HCl, diazo compounds A and B, and Benedict's reagent, among others. The discussion highlights the need for clarity on the functionalities of these reagents and their interactions with different organic compounds.

PREREQUISITES
  • Understanding of organic chemistry principles, particularly amine and alcohol reactions.
  • Familiarity with reagents such as p-DAB HCl and Benedict's reagent.
  • Knowledge of ketone chemistry, specifically reactions involving fructose.
  • Basic laboratory techniques for handling and reacting chemical substances.
NEXT STEPS
  • Research the reactivity of aromatic primary amines with p-DAB HCl.
  • Study the mechanisms of diazo compound reactions with alcohols.
  • Explore the significance of Benedict's reagent in ketone testing.
  • Investigate the chemical properties and reactions of Tetracycline and its derivatives.
USEFUL FOR

This discussion is beneficial for chemistry students, particularly those studying organic chemistry and medicinal chemistry, as well as educators and professionals involved in chemical research and laboratory practices.

wiraimperia
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Hello again, sorry I had been idle for months. At that time I was relatively active in the Physics section. Thank God now I'm at the Fac. of Medicine, University of Sriwijaya. In the beginning of my college we had a Chemistry Lab Practice and are assigned to make the report, in which the reactions below I'm blind and could not find after an intensive search on Google. Is there anybody who can help me (and probably my colleagues too) in answering these reactions?

Homework Statement


Make the reactions for:
a. Aromatic Primary Amine + p-DAB HCl
b. Alcohol + Diazo A
c. Alcohol + Diazo B
d. Ketone (Fructose) + [KOH boiled + I2]
e. Ketone (Fructose) + Na Nitropruside
f. Ketone (Fructose) + Benedict's reagent
g. Ethyl Ethanoate + H2O

h. Tetracyclin HCl + H2SO4
i. Tetracyclin HCl + FeCl3
j. Ampicillin, oxydated
k. Luminal Natrium (Luminal Sodium) + Cobalt Nitrate
l. Codein HCl + [H2SO4 + Formaldehyde]
m. Isoniazide (INH) + p-DAB HCl
n. Antalgin (Naproxen) + FeCl3
o. Caffeine + [KClO3 + HCl, burn to dehydrate, cool it down and add NH3]
p. Ephedrin HCl + [NaOH + CuSO4]
q. Sulfadiazine + p-DAB HCl
r. Sulfadiazine + [Dip a piece of wood in HCl, let it dry, and then dip the wood into Sulfadiazine]

Homework Equations


No equations

The Attempt at a Solution


No prior knowledge
 
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a) for instance, what functionality does p-DAB HCl have? Do any of those react with amines?