About ten years ago I began to experience leg cramps [really more of a severe ache] and sciatic pain in conjuction with moderate to severe bouts of the flu. And I don't mean discomfort, I mean crawling-out-of-my-skin pain. I've had three bouts like this in total, with yesterday being one of the most miserable days of my life. I assume that this results from inflamation, but inflamation of what, and why? Or, is there something besides inflamation that would cause this? Asprin or Tylenol don't even begin to take off the edge. Today I started on an anti-inflammatory in addition to NyQuil, which did finally help.